Gene expression profile in pelvic organ prolapse
نویسندگان
چکیده
منابع مشابه
Gene expression profile in pelvic organ prolapse.
It was hypothesized that the processes contributing to pelvic organ prolapse (POP) may be identified by transcriptional profiling of pelvic connective tissue in conjunction with light microscopy. In order to test this, we performed a frequency-matched case-control study of women undergoing hysterectomy for POP and controls. Total RNA, extracted from uterosacral and round ligament samples used t...
متن کاملPelvic organ prolapse.
Pelvic organ prolapse, or genital prolapse, is the descent of one or more of the pelvic structures (bladder, uterus, vagina) from the normal anatomic location toward or through the vaginal opening. Women of all ages may be affected, although pelvic organ prolapse is more common in older women. The cause is a loss of pelvic support from multiple factors, including direct injury to the levator an...
متن کاملPelvic organ prolapse.
The separate disease entities that are included in the general term of pelvic organ prolapse have been discussed in detail in this chapter. The focus of discussion centered on the pathophysiology and clinical presentation of these conditions. At this point, the emergency physician should be able to properly recognize, assess, initiate treatment, and obtain appropriate referral in cases of pelvi...
متن کاملDiminished vaginal HOXA13 expression in women with pelvic organ prolapse.
OBJECTIVE Homeobox genes are transcriptional regulators that orchestrate embryonic development. The HOXA13 gene is responsible for the development of the vagina and regulates extracellular matrix constituents. We hypothesized that vaginal expression of HOXA13 may be decreased in women with pelvic organ prolapse (POP) and sought to determine if hypoestrogenism affects its expression. METHODS B...
متن کاملRe: Sexual function in women with pelvic organ prolapse compared to women without pelvic organ prolapse.
PURPOSE We compared sexual function in women with pelvic organ prolapse to that in women without prolapse. MATERIALS AND METHODS We collected sexual function data using a standardized, validated, condition specific questionnaire. The study group consisted of 30 women with pelvic organ prolapse and it was compared with 30 unmatched controls without evidence of prolapse. RESULTS The 2 groups ...
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ژورنال
عنوان ژورنال: Molecular Human Reproduction
سال: 2008
ISSN: 1360-9947,1460-2407
DOI: 10.1093/molehr/gan074